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10.2146/ajhp110221 50 Kumar KulkarniA
IGF-1 LR3 in Stem Cell Self-Renewal Research Research has established that IGF-1 receptor signalling is necessary for human embryonic stem cell self-renewal, and that IGF-1 LR3 can substitute for native IGF-1 in stem cell cultures with increased potency and stability requiring lower concentrations for equivalent or superior biological effects compared to unmodified IGF-1
Given the historical pattern with obesity drug rollouts, patients should expect a slow and uneven coverage expansion
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